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Commercial Real Estate for Sale and Lease in Seneca, SC | Realty.com

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Commercial Real Estate for Sale and Lease in Seneca, SC

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3 of 27 Listings

Commercial Real Estate for Sale and Lease in Seneca, SC

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3 of 27 Listings

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Commercial Real Estate for Sale and Lease in Seneca, SC

3 of 27 Listings

9Active
$1,734,700
— bd · 0 ba · — sqft
31.54 Acres Frontage Road 31.66 Acres Keowee, Seneca, SC
Adrienne Hennes · RE/MAX Executive/Greenville
34Active
$219,000
— bd · 0 ba · — sqft
1510 Blue Ridge Boulevard, Seneca, SC
Cliff Powell · Powell Real Estate
29Active
$999,949
— bd · 0 ba · — sqft
235 Main Street, Seneca, SC
Adrienne Hennes · RE/MAX Executive/Greenville

1 2

Listing data & MLS disclosures

Western Upstate Multiple Listing Service: IDX information is provided exclusively for personal, non-commercial use, and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Information is deemed reliable but not guaranteed.
Listing information ©2026 Western Upstate Association of Realtors, Inc®. All Rights Reserved. Last Updated: 2026-09-18 17:11:05 UTC

Seneca, SC community profile

Population: 9,336
Median income: $54,836
Housing units: 4,482
People per sq. mi.: 68.4
Area: 136.4 sq. mi.

Source: HJN community data

L. Custen Realty, Inc. d/b/a Realty.com/L. Custen Realty CT, LLC d/b/a Realty.com (Tom O’Leary-Broker)(CT properties only), 8323 Southwest Freeway, Suite 900, Houston, Texas 77074

The information provided by this website is for the personal, non-commercial use of consumers and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Listing data is derived from various Multiple Listing Services; each source MLS and its required disclaimer are shown with the listings on the applicable page. Realty.com is an independently owned and operated brokerage.

Listing data & MLS disclosures

Western Upstate Multiple Listing Service: IDX information is provided exclusively for personal, non-commercial use, and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Information is deemed reliable but not guaranteed.
Listing information ©2026 Western Upstate Association of Realtors, Inc®. All Rights Reserved. Last Updated: 2026-09-18 17:11:05 UTC

Seneca, SC community profile

Population: 9,336
Median income: $54,836
Housing units: 4,482
People per sq. mi.: 68.4
Area: 136.4 sq. mi.

Source: HJN community data