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4 Bedroom Homes in Cape Girardeau, MO
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3 bedsNew constructionWith a pool

4 Bedroom Homes in Cape Girardeau, MO

4 Bedroom Homes in Cape Girardeau, MO

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24 of 36 Listings
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4 Bedroom Homes in Cape Girardeau, MO

24 of 36 Listings

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Thomas O'Leary

Realty.com

Lic. #2020001504

Call Thomas
  1. 1507 N Henderson Street — photo31Active

    $239,900

    4 bd · 2 ba · 1,662 sqft

    1507 N Henderson Street, Cape Girardeau, MO

    Kim Taylor · Area Properties Real Estate-River Region

  2. 142 Kingfisher Court — photo42Active

    $1,499,000

    4 bd · 5 ba · 5,100 sqft

    142 Kingfisher Court, Cape Girardeau, MO

    Casie Blattner · Area Properties Real Estate-River Region

  3. 2971 Pine Hill Spur — photo46Active

    $499,000

    4 bd · 3 ba · 2,588 sqft

    2971 Pine Hill Spur, Cape Girardeau, MO

    Caroline Ritter · Area Properties Real Estate-River Region

  4. 429 Emerald Street — photo5Active

    $225,000

    4 bd · 2 ba · 2,536 sqft

    429 Emerald Street, Cape Girardeau, MO

    Matt Millslagle · Salient Realty Group, LLC

  5. 1415 Themis Street — photo2Active

    $170,000

    4 bd · 2 ba · 1,945 sqft

    1415 Themis Street, Cape Girardeau, MO

    Matt Millslagle · Salient Realty Group, LLC

  6. 2715 Independence Street — photoPrice Reduced26Active

    $230,000

    4 bd · 3 ba · 2,488 sqft

    2715 Independence Street, Cape Girardeau, MO

    Ellen Kirchdoerfer · EDGE Realty, ERA Powered

  7. 1500 Pemiscot Street — photo6Active

    $184,900

    4 bd · 2 ba · 1,370 sqft

    1500 Pemiscot Street, Cape Girardeau, MO

    Casie Blattner · Area Properties Real Estate-River Region

  8. 723 N Missouri Street — photo1Active

    $189,900

    4 bd · 2 ba · 1,781 sqft

    723 N Missouri Street, Cape Girardeau, MO

    Casie Blattner · Area Properties Real Estate-River Region

  9. 1848 Thilenius Street — photoPrice Reduced19Active

    $205,000

    4 bd · 2 ba · 1,696 sqft

    1848 Thilenius Street, Cape Girardeau, MO

    Tara Newell-Koehler · Century 21 Ashland Realty

  10. 216 Timber Hawk Trail — photo32Active

    $345,000

    4 bd · 3 ba · 2,275 sqft

    216 Timber Hawk Trail, Cape Girardeau, MO

    Amber Prasanphanich · EDGE Realty ERA Powered

  11. 2537 Jonquil Lane — photo46Active

    $299,000

    4 bd · 3 ba · 2,398 sqft

    2537 Jonquil Lane, Cape Girardeau, MO

    Drake Bentley · Ritter Real Estate

  12. 325 N Main Street — photo47Active

    $575,000

    4 bd · 5 ba · 3,578 sqft

    325 N Main Street, Cape Girardeau, MO

    Dana Shirrell · EPM Real Estate

  13. 2625 Liberty Court — photoPrice Reduced50Active

    $420,000

    4 bd · 3 ba · 2,936 sqft

    2625 Liberty Court, Cape Girardeau, MO

    Carrie Stroup · EDGE Realty ERA Powered

  14. 1202 S Sprigg Street — photo6Active

    $55,000

    4 bd · 6 ba · 4,428 sqft

    1202 S Sprigg Street, Cape Girardeau, MO

    Renee Reyes · Main Key Realty, LLC

  15. 859 Lochinvar Lane — photoPrice Reduced46Active

    $440,000

    4 bd · 3 ba · 2,470 sqft

    859 Lochinvar Lane, Cape Girardeau, MO

    Kristal Flentge · EDGE Realty ERA Powered

  16. 1721 William Street — photo41Active

    $180,000

    4 bd · 2 ba · 1,674 sqft

    1721 William Street, Cape Girardeau, MO

    Kristal Flentge · EDGE Realty ERA Powered

  17. 1807 Ricardo Drive — photoPrice Reduced21Active

    $235,000

    4 bd · 3 ba · 1,612 sqft

    1807 Ricardo Drive, Cape Girardeau, MO

    Tasha Cardin · EXP Realty, LLC

  18. 2642 Liberty Court — photoPrice Reduced42Active

    $479,900

    4 bd · 3 ba · 3,028 sqft

    2642 Liberty Court, Cape Girardeau, MO

    Angela Womack · Paul Kitchen & Associates

  19. 616 Jefferson Avenue — photo1Active

    $89,900

    4 bd · 2 ba · 1,104 sqft

    616 Jefferson Avenue, Cape Girardeau, MO

    Alan Wengert · EDGE Realty ERA Powered

  20. 612 Jefferson Avenue — photo1Active

    $89,900

    4 bd · 2 ba · 1,104 sqft

    612 Jefferson Avenue, Cape Girardeau, MO

    Alan Wengert · EDGE Realty ERA Powered

  21. 1863 Greenbrier Street — photoPrice Reduced59Active

    $458,000

    4 bd · 3 ba · 3,302 sqft

    1863 Greenbrier Street, Cape Girardeau, MO

    Lois Long · EDGE Realty ERA Powered

  22. 3926 Annwood Drive — photoPrice Reduced68Active

    $749,900

    4 bd · 5 ba · 3,528 sqft

    3926 Annwood Drive, Cape Girardeau, MO

    Terri Penrod · EDGE Realty ERA Powered

  23. 1301 Jefferson Avenue — photoPrice Reduced11Active

    $159,900

    4 bd · 2 ba · 2,366 sqft

    1301 Jefferson Avenue, Cape Girardeau, MO

    Elizabeth McFerron · Main Key Realty, LLC

  24. 3214 Lakewood Drive — photoPrice Reduced59Active

    $635,000

    4 bd · 5 ba · 4,363 sqft

    3214 Lakewood Drive, Cape Girardeau, MO

    Debra Martin · EDGE Realty, ERA Powered

12

Explore Cape Girardeau homes

By price

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The information provided by this website is for the personal, non-commercial use of consumers and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Listing data is derived from various Multiple Listing Services; each source MLS and its required disclaimer are shown with the listings on the applicable page. Realty.com is an independently owned and operated brokerage.

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Listing data & MLS disclosures

MARIS MLS
Based on information submitted to the MLS GRID as of 2026-09-20 05:33:13 UTC. All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information.
  • Multi-family homes
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    Your local brokerage

    TO

    Thomas O'Leary

    Realty.com

    Lic. #2020001504

    Call Thomas

    Cape Girardeau, MO community profile

    Population
    40,558
    Median income
    $51,981
    Housing units
    18,456
    People per sq. mi.
    286.8
    Area
    141.4 sq. mi.

    Source: HJN community data

    Cape Girardeau housing market

    August 2026 · This period is still settling

    Homes on the market · MLS, as of Aug 31, 2026

    Median list price
    $240,000
    Homes for sale
    159
    Median days on market
    35 days

    Price trend · Assessor repeat sales, as of Aug 31, 2026

    Year-over-year
    -6.8%

    Housing stock — every home in the area, not only the ones selling or listed · Assessor records, as of Jul 29, 2026

    Median home size
    1,547 sq. ft.