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Commercial Real Estate for Sale and Lease in Cape Girardeau, MO | Realty.com
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97 listings
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Commercial Real Estate for Sale and Lease in Cape Girardeau, MO

Commercial Real Estate for Sale and Lease in Cape Girardeau, MO

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24 of 97 Listings
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Commercial Real Estate for Sale and Lease in Cape Girardeau, MO

24 of 97 Listings

  1. 3 S Broadview — photo7Active

    $125,000

    0 bd · 0 ba · — sqft

    3 S Broadview, Cape Girardeau, MO

    Casie Blattner · Area Properties Real Estate-River Region

  2. Lot #19 Independence Street — photo11Active

    $218,500

    0 bd · 0 ba · — sqft

    Lot #19 Independence Street, Cape Girardeau, MO

    Casie Blattner · Area Properties Real Estate-River Region

  3. Lot #4 West Drive — photo11Active

    $212,500

    0 bd · 0 ba · — sqft

    Lot #4 West Drive, Cape Girardeau, MO

    Casie Blattner · Area Properties Real Estate-River Region

  4. Lot #3 West Drive — photo11Active

    $212,500

    0 bd · 0 ba · — sqft

    Lot #3 West Drive, Cape Girardeau, MO

    Casie Blattner · Area Properties Real Estate-River Region

  5. 26 N Spanish Street — photo39Active

    $975,000

    0 bd · 0 ba · 10,850 sqft

    26 N Spanish Street, Cape Girardeau, MO

    Chris Cole · Lorimont L.C.

  6. 10 S Spanish Street — photo56Active

    $2,500,000

    0 bd · 0 ba · 14,436 sqft

    10 S Spanish Street, Cape Girardeau, MO

    Mary Knote · EDGE Realty ERA Powered

  7. 201-301 S Broadview Street — photo26Active

    $4,950,000

    0 bd · 0 ba · 81,605 sqft

    201-301 S Broadview Street, Cape Girardeau, MO

    Matthew Huber · Lorimont L.C.

  8. 1000 Kingsway Drive — photo23Active

    $2,348/mo

    0 bd · 0 ba · 1,740 sqft

    1000 Kingsway Drive, Cape Girardeau, MO

    Amber Prasanphanich · EDGE Realty ERA Powered

  9. 1000 Kingsway Drive 1 — photo23Active

    $1,885/mo

    0 bd · 0 ba · 1,370 sqft

    1000 Kingsway Drive 1, Cape Girardeau, MO

    Amber Prasanphanich · EDGE Realty ERA Powered

  10. 710 Southern Expressway — photo45Active

    $475,000

    0 bd · 0 ba · 17,496 sqft

    710 Southern Expressway, Cape Girardeau, MO

    Chelsea Dillick · EXP Realty, LLC

  11. 2117 Broadway Street Suite B — photo23Active

    $1,900/mo

    0 bd · 0 ba · — sqft

    2117 Broadway Street Suite B, Cape Girardeau, MO

    Matthew Huber · Lorimont L.C.

  12. 2905 Independence Street Suite D — photo12Active

    $800/mo

    0 bd · 0 ba · — sqft

    2905 Independence Street Suite D, Cape Girardeau, MO

    Lawren McMullan · EDGE Realty, ERA Powered

  13. 1931 N Kingshighway Street — photo24Active

    $459,000

    0 bd · 0 ba · 1,000 sqft

    1931 N Kingshighway Street, Cape Girardeau, MO

    Sandy Tegel · Century 21 Ashland Realty

  14. 627/635 S Sprigg Street — photo8Active

    $450,000

    0 bd · 0 ba · — sqft

    627/635 S Sprigg Street, Cape Girardeau, MO

    Jessica Moore · EXP Realty, LLC

  15. 631 S Sprigg Street — photo1Active

    $250,000

    0 bd · 0 ba · — sqft

    631 S Sprigg Street, Cape Girardeau, MO

    Jessica Moore · EXP Realty, LLC

  16. 760 S Kingshighway E — photo13Active

    $1,300/mo

    0 bd · 0 ba · — sqft

    760 S Kingshighway E, Cape Girardeau, MO

    Tom Kelsey · Lorimont L.C.

  17. 760 S Kingshighway H — photo15Active

    $4,500/mo

    0 bd · 0 ba · — sqft

    760 S Kingshighway H, Cape Girardeau, MO

    Tom Kelsey · Lorimont L.C.

  18. 760 S Kingshighway K — photo21Active

    $3,120/mo

    0 bd · 0 ba · — sqft

    760 S Kingshighway K, Cape Girardeau, MO

    Tom Kelsey · Lorimont L.C.

  19. 760 S Kingshighway C — photo4Active

    $4,995/mo

    0 bd · 0 ba · — sqft

    760 S Kingshighway C, Cape Girardeau, MO

    Tom Kelsey · Lorimont L.C.

  20. 1020 N Kingshighway Street C — photo9Active

    $1,200/mo

    0 bd · 0 ba · — sqft

    1020 N Kingshighway Street C, Cape Girardeau, MO

    Tom Kelsey · Lorimont L.C.

  21. 1736 Broadway Street — photoPrice Reduced28Active

    $7,000/mo

    0 bd · 0 ba · 9,696 sqft

    1736 Broadway Street, Cape Girardeau, MO

    Caroline Ritter · Area Properties Real Estate-River Region

  22. 1980 Golden Eagle Court — photo1Active

    $395,000

    0 bd · 0 ba · — sqft

    1980 Golden Eagle Court, Cape Girardeau, MO

    Jacob Fish · EDGE Realty ERA Powered

  23. 1400 N Sprigg Street — photo1Active

    $945,000

    0 bd · 0 ba · — sqft

    1400 N Sprigg Street, Cape Girardeau, MO

    Tammy Kwikkel-Bucher · EDGE Realty ERA Powered

  24. 1461 N Kingshighway Street — photo13Active

    $2,255/mo

    0 bd · 0 ba · — sqft

    1461 N Kingshighway Street, Cape Girardeau, MO

    Lauren Marshall · Century 21 Ashland Realty

12…5
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Listing data & MLS disclosures

MARIS MLS
Based on information submitted to the MLS GRID as of 2026-10-22 18:31:39 UTC. All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information.

Cape Girardeau, MO community profile

Population
40,558
Median income
$51,981
Housing units
18,456
People per sq. mi.
286.8
Area
141.4 sq. mi.

Source: HJN community data