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Commercial Real Estate for Sale and Lease in Cape Girardeau, MO | Realty.com
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93 listings
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Commercial Real Estate for Sale and Lease in Cape Girardeau, MO

Commercial Real Estate for Sale and Lease in Cape Girardeau, MO

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24 of 93 Listings
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Commercial Real Estate for Sale and Lease in Cape Girardeau, MO

24 of 93 Listings

  1. 2905 Independence Street Suite D — photo12Active

    $800/mo

    — bd · — ba · — sqft

    2905 Independence Street Suite D, Cape Girardeau, MO

    Lawren McMullan · EDGE Realty, ERA Powered

  2. 1931 N Kingshighway Street — photo3Active

    $459,000

    — bd · — ba · — sqft

    1931 N Kingshighway Street, Cape Girardeau, MO

    Sandy Tegel · Century 21 Ashland Realty

  3. 627/635 S Sprigg Street — photo8Active

    $450,000

    — bd · — ba · — sqft

    627/635 S Sprigg Street, Cape Girardeau, MO

    Jessica Moore · EXP Realty, LLC

  4. 631 S Sprigg Street — photo1Active

    $250,000

    — bd · — ba · — sqft

    631 S Sprigg Street, Cape Girardeau, MO

    Jessica Moore · EXP Realty, LLC

  5. 760 S Kingshighway C — photo4Active

    $4,995/mo

    — bd · — ba · — sqft

    760 S Kingshighway C, Cape Girardeau, MO

    Tom Kelsey · Lorimont L.C.

  6. 760 S Kingshighway H — photo15Active

    $4,500/mo

    — bd · — ba · — sqft

    760 S Kingshighway H, Cape Girardeau, MO

    Tom Kelsey · Lorimont L.C.

  7. 760 S Kingshighway E — photo13Active

    $1,300/mo

    — bd · — ba · — sqft

    760 S Kingshighway E, Cape Girardeau, MO

    Tom Kelsey · Lorimont L.C.

  8. 760 S Kingshighway K — photo21Active

    $3,120/mo

    — bd · — ba · — sqft

    760 S Kingshighway K, Cape Girardeau, MO

    Tom Kelsey · Lorimont L.C.

  9. 1020 N Kingshighway Street C — photo9Active

    $1,200/mo

    — bd · — ba · — sqft

    1020 N Kingshighway Street C, Cape Girardeau, MO

    Tom Kelsey · Lorimont L.C.

  10. 1736 Broadway Street — photo28Active

    $8,000/mo

    — bd · — ba · — sqft

    1736 Broadway Street, Cape Girardeau, MO

    Caroline Ritter · Area Properties Real Estate-River Region

  11. 1980 Golden Eagle Court — photo1Active

    $395,000

    — bd · — ba · — sqft

    1980 Golden Eagle Court, Cape Girardeau, MO

    Jacob Fish · EDGE Realty ERA Powered

  12. 1400 N Sprigg Street — photo1Active

    $945,000

    — bd · — ba · — sqft

    1400 N Sprigg Street, Cape Girardeau, MO

    Tammy Kwikkel-Bucher · EDGE Realty ERA Powered

  13. 1469 N Kingshighway Street — photo10Active

    $1,128/mo

    — bd · — ba · — sqft

    1469 N Kingshighway Street, Cape Girardeau, MO

    Lauren Marshall · Century 21 Ashland Realty

  14. 0 Rear Commercial Street — photo18Active

    $345,000

    — bd · — ba · — sqft

    0 Rear Commercial Street, Cape Girardeau, MO

    William Penrod · EDGE Realty ERA Powered

  15. 1461 N Kingshighway Street — photo13Active

    $2,255/mo

    — bd · — ba · — sqft

    1461 N Kingshighway Street, Cape Girardeau, MO

    Lauren Marshall · Century 21 Ashland Realty

  16. 333 N Main Street — photo39Active

    $425,000

    — bd · — ba · — sqft

    333 N Main Street, Cape Girardeau, MO

    Jacob Fish · EDGE Realty ERA Powered

  17. 525 Broadway Street — photo9Active

    $189,000

    — bd · — ba · — sqft

    525 Broadway Street, Cape Girardeau, MO

    Jacob Fish · EDGE Realty ERA Powered

  18. 225 Clark Avenue — photo21Active

    $250,000

    — bd · — ba · — sqft

    225 Clark Avenue, Cape Girardeau, MO

    Jessica Moore · EXP Realty, LLC

  19. 312 Bellevue Street — photo33Active

    $545,000

    — bd · — ba · — sqft

    312 Bellevue Street, Cape Girardeau, MO

    Lindsay Cauble · Ritter Real Estate

  20. 45 S Kingshighway — photoPrice Reduced2Active

    $2,500,000

    — bd · — ba · — sqft

    45 S Kingshighway, Cape Girardeau, MO

    Michelle Quade · Century 21 Ashland Realty

  21. 2552 Independence Street — photo1Active

    $2,000/mo

    — bd · — ba · — sqft

    2552 Independence Street, Cape Girardeau, MO

    Jim Rampley · Semo Home Realty

  22. 1926 N Kingshighway Street — photoPrice Reduced4Active

    $580,000

    — bd · — ba · — sqft

    1926 N Kingshighway Street, Cape Girardeau, MO

    Jim Rampley · Semo Home Realty

  23. 5 S Kingshighway — photo21Active

    $8,707/mo

    — bd · — ba · — sqft

    5 S Kingshighway, Cape Girardeau, MO

    Tom Kelsey · Lorimont L.C.

  24. 213 Clark Avenue — photo12Active

    $1,500/mo

    — bd · — ba · — sqft

    213 Clark Avenue, Cape Girardeau, MO

    Chris Cole · Lorimont L.C.

12…4
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Listing data & MLS disclosures

MARIS MLS
Based on information submitted to the MLS GRID as of 2026-09-07 05:34:25 UTC. All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information.

Cape Girardeau, MO community profile

Population
40,558
Median income
$51,981
Housing units
18,456
People per sq. mi.
286.8
Area
141.4 sq. mi.

Source: HJN community data