Start here

Homes for sale by state
Home buying tips
Before you start looking
The buying timeline

Afford it

Today's mortgage rates
Mortgage calculator
How much can I afford?
Get pre-approved

Make the deal

Writing a winning offer
Inspections & appraisals
Closing costs, itemized
Find a buyer's agent

Selling Options

What's my home worth?
Compare selling options
Get an instant cash offer
Buy before you sell

Resources

How selling works
When should I sell?
Home selling tips
Pricing your home
What's worth fixing first
Find a seller's agent

Save search Advertise Sign In

Saved homes Saved searches Your tours Your inquiries Recently viewed Account settings

Registered offenders on the map

Show registered offenders (Florida and Texas)

Registered offenders on the map

Show registered offenders (Florida and Texas)

Safety & registry resources

Review official public-safety information for any area from these government sources:

U.S. Dept. of Justice National Sex Offender Public Website (NSOPW)
FBI: state sex-offender registry directory

Start here

Homes for sale by state
Home buying tips
Before you start looking
The buying timeline

Afford it

Today's mortgage rates
Mortgage calculator
How much can I afford?
Get pre-approved

Make the deal

Writing a winning offer
Inspections & appraisals
Closing costs, itemized
Find a buyer's agent

Save search Advertise Sign In

Saved homes Saved searches Your tours Your inquiries Recently viewed Account settings

Registered offenders on the map

Show registered offenders (Florida and Texas)

Selling Options

What's my home worth?
Compare selling options
Get an instant cash offer
Buy before you sell

Resources

How selling works
When should I sell?
Home selling tips
Pricing your home
What's worth fixing first
Find a seller's agent

261 listings

Homes for Sale in 49221, MI

Homes for Sale in 49221, MI

15 of 261 Listings

Homes for Sale in 49221, MI

15 of 261 Listings

23Active

$75,000

3 bd · 2 ba · 1,566 sqft

170 Newbury, Adrian City, MI

Trista Williams · EXP Realty Main

$622,450

3 bd · 4 ba · 3,203 sqft

2156 Heatherwood Drive, Adrian Township, MI

Donald Page · DJW Realty, LLC

$49,000

3 bd · 2 ba · 1,344 sqft

409 Colorado River Drive, Adrian City, MI

Trista Williams · EXP Realty Main

$600,000

3 bd · 3 ba · 3,522 sqft

5750 Lyons Highway, Madison Charter Township, MI

Shirley Smith · Howard Hanna Real Estate Services-Adrian

$299,900

3 bd · 2 ba · 1,764 sqft

380 S Scott Street, Adrian City, MI

Christopher Coscarelli · Foundation Realty, LLC - Manitou Beach

$329,900

3 bd · 3 ba · 2,029 sqft

3394 W Circle Drive, Adrian Township, MI

Mary Clymer · Heart O' The Hills Realty

$170,000

2 bd · 1 ba · 1,160 sqft

810 Division Street, Adrian City, MI

Tim Bender · TLB Realty LLC

$109,900

3 bd · 1 ba · 1,230 sqft

546 Northwestern Drive, Adrian, MI

Tamra Allen · Production Realty

$293,900

3 bd · 2 ba · 1,324 sqft

2010 Green Acres Drive, Adrian, MI

Donald Page · DJW Realty, LLC

$328,000

3 bd · 3 ba · 1,780 sqft

2024 Green Acres Drive, Adrian, MI

Donald Page · DJW Realty, LLC

$300,800

3 bd · 2 ba · 1,268 sqft

2022 Green Acres Drive, Adrian, MI

Donald Page · DJW Realty, LLC

Price Reduced19Active

$320,300

3 bd · 3 ba · 1,648 sqft

2018 Green Acres Drive, Adrian, MI

Donald Page · DJW Realty, LLC

$425,000

3 bd · 2 ba · 2,056 sqft

2150 Southard Highway, Adrian City, MI

Lesley Dempsey · Howard Hanna Real Estate Services-Adrian

Price Reduced40Active

$204,900

2 bd · 1 ba · 1,134 sqft

312 W Summit Street, Adrian City, MI

Laura Hayes · Howard Hanna Real Estate Services-Tecumseh

$269,900

4 bd · 2 ba · 1,396 sqft

972 Gettysburg Drive, Adrian City, MI

Kay Buenaflor Prong · Howard Hanna Real Estate Services-Tecumseh

1 2 3 4…11

L. Custen Realty, Inc. d/b/a Realty.com/L. Custen Realty CT, LLC d/b/a Realty.com (Tom O’Leary-Broker)(CT properties only), 8323 Southwest Freeway, Suite 900, Houston, Texas 77074

The information provided by this website is for the personal, non-commercial use of consumers and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Listing data is derived from various Multiple Listing Services; each source MLS and its required disclaimer are shown with the listings on the applicable page. Realty.com is an independently owned and operated brokerage.

© 2026 Realty.com. All rights reserved.PrivacyTermsCalifornia Privacy RightsAccessibilityLicensing

Listing data & MLS disclosures

MiRealSource: Provided through IDX via MiRealSource. Courtesy of MiRealSource Shareholder. The information published and disseminated by MiRealSource is communicated verbatim, without change by MiRealSource, as filed with MiRealSource by its members. The accuracy of all information, regardless of source, is not guaranteed or warranted. All information should be independently verified. Copyright [current year] MiRealSource. All rights reserved. The information provided hereby constitutes proprietary information of MiRealSource, Inc. and its shareholders, affiliates and licensees and may not be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, scanning or any information storage and retrieval system, without written permission from MiRealSource, Inc.
Realcomp: IDX provided courtesy of Realcomp II Ltd. via Realty.com and Realcomp MLS, ©2026 Realcomp II Ltd. Shareholders The accuracy of all information, regardless of source, is not guaranteed or warranted. All information should be independently verified. Any use of search facilities of data on the site, other than by a consumer looking to purchase real estate, is prohibited.
Southwestern Michigan Association of REALTORS: The properties on this website come in part from the Broker Reciprocity Program of the Member MLS's of the Michigan Regional Information Center. Information Deemed Reliable But Not Guaranteed. The firm operating this website does not display the entire MLS, MichRIC, LLC, Broker Reciprocity database on this website. Any use of search facilities of data on the site, other than by a consumer looking to purchase real estate, is prohibited. Information deemed reliable but not guaranteed. Copyright ©2026 Michigan Regional Information Center. All Rights Reserved.

49221, MI Homes for Sale — Page 3 | Realty.com

Nearby areas

ZIP codes

49203 (238)
48176 (237)
48108 (199)
49230 (143)
49201 (103)
48197 (101)
48158 (82)
48160 (75)

Cities

Jackson (230)
Ann Arbor (169)
Adrian (149)
Saline (144)
Brooklyn (94)

Pittsfield Charter Township (92)

Jackson City (65)

Adrian City (57)