Start here

Homes for sale by state
Home buying tips
Before you start looking
The buying timeline

Afford it

Today's mortgage rates
Mortgage calculator
How much can I afford?
Get pre-approved

Make the deal

Writing a winning offer
Inspections & appraisals
Closing costs, itemized
Find a buyer's agent

Sell

Selling Options

What's my home worth?
Compare selling options
Get an instant cash offer
Buy before you sell

Resources

How selling works
When should I sell?
Home selling tips
Pricing your home
What's worth fixing first
Find a seller's agent

Home Loans

Find an Agent

Save search Advertise Sign In

Saved homes Saved searches Your tours Your inquiries Recently viewed Account settings

Save search

Map layers

Safety

Sex offendersRegistered offenders, from official state registriesCamerasLicense-plate readers, CCTV and more, as mapped on OpenStreetMap

Safety & registry resources

Review official public-safety information for any area from these government sources:

U.S. Dept. of Justice National Sex Offender Public Website (NSOPW)
FBI: state sex-offender registry directory

Buy

Start here

Homes for sale by state
Home buying tips
Before you start looking
The buying timeline

Afford it

Today's mortgage rates
Mortgage calculator
How much can I afford?
Get pre-approved

Make the deal

Writing a winning offer
Inspections & appraisals
Closing costs, itemized
Find a buyer's agent

Save search Advertise Sign In

Saved homes Saved searches Your tours Your inquiries Recently viewed Account settings

203 listings

Sell

Selling Options

What's my home worth?
Compare selling options
Get an instant cash offer
Buy before you sell

Resources

How selling works
When should I sell?
Home selling tips
Pricing your home
What's worth fixing first
Find a seller's agent

Home Loans

Find an Agent

Save search

203 listings

Homes for Sale in 49221, MI

Hide Map

20 of 203 Listings

Map

20 of 203 Listings

Price Reduced38Active

$160,000

3 bd · 2 ba · 1,522 sqft

612 N Clinton Street, Adrian, MI

Jessica Roddy · Xsell Realty

17Active

$581,000

3 bd · 4 ba · 2,642 sqft

4892 Thompson Heights Drive, Adrian, MI

20Active

$124,900

3 bd · 1 ba · 910 sqft

634 Grand Street, Adrian, MI

13Active

$453,400

3 bd · 2 ba · 2,019 sqft

4909 Schmitz Court, Adrian, MI

56Active

$795,000

4 bd · 4 ba · 3,472 sqft

4400 Douglas Drive, Adrian, MI

14Active

$119,900

3 bd · 2 ba · 986 sqft

122 W Beecher Street, Adrian, MI

43Active

$458,500

4 bd · 4 ba · 2,509 sqft

4823 Thompson Heights Drive, Adrian, MI

44Active

$300,000

4 bd · 2 ba · 1,963 sqft

4079 Bennett Court, Adrian, MI

Michael Knox · Xsell Realty

5Active

$169,900

4 bd · 2 ba · 2,000 sqft

115 S Mckenzie Street S, Adrian, MI

Jaime Gerig Poling · Gerig Realty

33Active

$79,900

4 bd · 1 ba · 1,572 sqft

665 Dennis Street, Adrian, MI

56Active

$299,900

3 bd · 2 ba · 1,877 sqft

2930 Spielman Road, Adrian, MI

5Active

$169,900

4 bd · 2 ba · 2,000 sqft

115 S Mckenzie Street, Adrian, MI

59Active

$399,900

4 bd · 3 ba · 1,996 sqft

3659 Tanner Marie Drive, Adrian, MI

37Active

$205,000

3 bd · 2 ba · 2,202 sqft

611 State Street, Adrian, MI

Price Reduced33Active

$245,000

5 bd · 2 ba · 2,394 sqft

349 S Main Street, Adrian, MI

SanJuanita Navarro · Xsell Realty

Price Reduced44Active

$195,500

3 bd · 2 ba · 1,362 sqft

1231 Vine Street, Adrian, MI

34Active

$324,900

4 bd · 3 ba · 1,949 sqft

3309 Birch Run, Adrian, MI

39Active

$235,000

3 bd · 2 ba · 1,675 sqft

129 E Butler Street, Adrian, MI

62Active

$324,900

3 bd · 2 ba · 2,000 sqft

1241 E Oregon Road, Adrian, MI

24Active

$62,500

3 bd · 2 ba · 910 sqft

80 Sterling, Adrian, MI

Jeffrey Rising · Cornerstone Real Estate

1 2 3…9

Listing data & MLS disclosures

MiRealSource: Provided through IDX via MiRealSource. Courtesy of MiRealSource Shareholder. The information published and disseminated by MiRealSource is communicated verbatim, without change by MiRealSource, as filed with MiRealSource by its members. The accuracy of all information, regardless of source, is not guaranteed or warranted. All information should be independently verified. Copyright [current year] MiRealSource. All rights reserved. The information provided hereby constitutes proprietary information of MiRealSource, Inc. and its shareholders, affiliates and licensees and may not be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, scanning or any information storage and retrieval system, without written permission from MiRealSource, Inc.
Southwestern Michigan Association of REALTORS: The properties on this website come in part from the Broker Reciprocity Program of the Member MLS's of the Michigan Regional Information Center. Information Deemed Reliable But Not Guaranteed. The firm operating this website does not display the entire MLS, MichRIC, LLC, Broker Reciprocity database on this website. Any use of search facilities of data on the site, other than by a consumer looking to purchase real estate, is prohibited. Information deemed reliable but not guaranteed. Copyright ©2026 Michigan Regional Information Center. All Rights Reserved.

Nearby areas

ZIP codes

49203 (268)
48176 (207)
48108 (141)
49230 (124)
49201 (106)
49286 (73)
48158 (66)
48197 (62)

Cities

Jackson (360)
Adrian (197)
Saline (194)
Ann Arbor (153)
Brooklyn (112)
Tecumseh (67)
Manchester (61)
Ypsilanti (54)

L. Custen Realty, Inc. d/b/a Realty.com/L. Custen Realty CT, LLC d/b/a Realty.com (Tom O’Leary-Broker)(CT properties only), 8323 Southwest Freeway, Suite 900, Houston, Texas 77074

The information provided by this website is for the personal, non-commercial use of consumers and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Listing data is derived from various Multiple Listing Services; each source MLS and its required disclaimer are shown with the listings on the applicable page. Realty.com is an independently owned and operated brokerage.

Listing data & MLS disclosures

MiRealSource: Provided through IDX via MiRealSource. Courtesy of MiRealSource Shareholder. The information published and disseminated by MiRealSource is communicated verbatim, without change by MiRealSource, as filed with MiRealSource by its members. The accuracy of all information, regardless of source, is not guaranteed or warranted. All information should be independently verified. Copyright [current year] MiRealSource. All rights reserved. The information provided hereby constitutes proprietary information of MiRealSource, Inc. and its shareholders, affiliates and licensees and may not be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, scanning or any information storage and retrieval system, without written permission from MiRealSource, Inc.
Southwestern Michigan Association of REALTORS: The properties on this website come in part from the Broker Reciprocity Program of the Member MLS's of the Michigan Regional Information Center. Information Deemed Reliable But Not Guaranteed. The firm operating this website does not display the entire MLS, MichRIC, LLC, Broker Reciprocity database on this website. Any use of search facilities of data on the site, other than by a consumer looking to purchase real estate, is prohibited. Information deemed reliable but not guaranteed. Copyright ©2026 Michigan Regional Information Center. All Rights Reserved.

49221, MI Homes for Sale — Page 2 | Realty.com

Nearby areas

ZIP codes

49203 (268)
48176 (207)
48108 (141)
49230 (124)
49201 (106)
49286 (73)
48158 (66)
48197 (62)

Cities

Jackson (360)
Adrian (197)
Saline (194)
Ann Arbor (153)
Brooklyn (112)
Tecumseh (67)
Manchester (61)
Ypsilanti (54)