Map location of
Big Sister Key Preserve, Lee County, FL, USA

Florida, United States

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Homes for sale near Big Sister Key Preserve, Lee County, FL, USA

Address Bed / Bath Listing Price
Picture of 2499 Sapodilla Lane
2499 Sapodilla Lane
Just the perfect latitude for your new island attitude. This stunning gulf access home was completely remodeled in 2023. As you head in, the custom tile wall with inlay shelves and built-in electric fireplace sets the tone of style and island luxury. It doesn’t stop there…the custom kitchen with
Other, FL
Living Area: 1386 Sqft.
3 Beds, 2 Baths
$750,000
Picture of 2499 Sapodilla LN
2499 Sapodilla LN
Just the perfect latitude for your new island attitude. This stunning gulf access home was completely remodeled in 2023. As you head in, the custom tile wall with inlay shelves and built-in electric fireplace sets the tone of style and island luxury. It doesn’t stop there…the custom kitchen with
OTHER, FL
Living Area: 1386 Sqft.
3 Beds, 2 Baths
$750,000
Picture of 2357 Sapodilla LN
2357 Sapodilla LN
SAILORS AND POWER BOATERS WANTED!!! This stunning and completely remodeled waterfront three-story pool home is a water enthusiast’s paradise! Be on the ICW or the Gulf of Mexico within minutes, with no bridges or locks to navigate. The extensive waterfront is comprised of a large 14’ x 40’ sli
ST. JAMES CITY, FL
Living Area: 1877 Sqft.
3 Beds, 2 Baths
$1,375,000
Picture of 2357 Sapodilla Lane
2357 Sapodilla Lane
SAILORS AND POWER BOATERS WANTED!!! This stunning and completely remodeled waterfront three-story pool home is a water enthusiast’s paradise! Be on the ICW or the Gulf of Mexico within minutes, with no bridges or locks to navigate. The extensive waterfront is comprised of a large 14’ x 40’ sli
St James City, FL
Living Area: 1877 Sqft.
3 Beds, 2 Baths
$1,375,000
Picture of 2192 8th AVE
2192 8th AVE
Experience Breathtaking Gulf and Bay Views from this Fully Renovated Pine Island Treasure! Prepare to be captivated by expansive vistas that stretch across both the Gulf and the Bay—an ever-changing backdrop of water, wildlife, and wonder. This exceptional residence offers direct Gulf access and
ST. JAMES CITY, FL
Living Area: 1748 Sqft.
2 Beds, 3 Baths
$1,179,000
Picture of 2192 8th Avenue
2192 8th Avenue
Experience Breathtaking Gulf and Bay Views from this Fully Renovated Pine Island Treasure! Prepare to be captivated by expansive vistas that stretch across both the Gulf and the Bay—an ever-changing backdrop of water, wildlife, and wonder. This exceptional residence offers direct Gulf access and
St James City, FL
Living Area: 1748 Sqft.
2 Beds, 3 Baths
$1,179,000
Picture of 2272 Macadamia LN
2272 Macadamia LN
Step into a world where every sunrise paints the sky with pastel hues and every sunset sets the horizon ablaze with fiery brilliance. Welcome to your own sanctuary, where whimsy meets luxury in perfect harmony. Nestled along the picturesque Bay Front, this enchanting residence boasts five private en
ST. JAMES CITY, FL
Living Area: 3766 Sqft.
5 Beds, 6 Baths
$1,699,995
Picture of 2272 Macadamia Lane
2272 Macadamia Lane
Step into a world where every sunrise paints the sky with pastel hues and every sunset sets the horizon ablaze with fiery brilliance. Welcome to your own sanctuary, where whimsy meets luxury in perfect harmony. Nestled along the picturesque Bay Front, this enchanting residence boasts five private en
St James City, FL
Living Area: 3766 Sqft.
5 Beds, 6 Baths
$1,699,995
Picture of 2420 Cherimoya LN
2420 Cherimoya LN
NO FLOODING! LIVE THE DREAM WITH MINUTES OUT TO OPEN WATERS! Welcome to your dream waterfront home in beautiful St. James City! This fully remodeled 4-bedroom, 4-bath residence offers unparalleled luxury and comfort. Nestled on a direct access canal, a true boater's paradise with a 10,000-pound boat
ST. JAMES CITY, FL
Living Area: 2157 Sqft.
4 Beds, 4 Baths
$1,149,000
Picture of 2420 Cherimoya Lane
2420 Cherimoya Lane
NO FLOODING! LIVE THE DREAM WITH MINUTES OUT TO OPEN WATERS! Welcome to your dream waterfront home in beautiful St. James City! This fully remodeled 4-bedroom, 4-bath residence offers unparalleled luxury and comfort. Nestled on a direct access canal, a true boater's paradise with a 10,000-pound boat
St James City, FL
Living Area: 2157 Sqft.
4 Beds, 4 Baths
$1,149,000
Picture of 2324 Cherimoya LN
2324 Cherimoya LN
This waterfront gem has been lovingly cared for, with every detail reflecting the pride of ownership and meticulous attention to maintenance. Direct, deep-water Gulf access pool home, perfectly positioned just minutes from Pine Island Sound and the Intracoastal Waterway. Offering easy access to back
ST. JAMES CITY, FL
Living Area: 2016 Sqft.
3 Beds, 2 Baths
$999,500
Picture of 2324 Cherimoya Lane
2324 Cherimoya Lane
This waterfront gem has been lovingly cared for, with every detail reflecting the pride of ownership and meticulous attention to maintenance. Direct, deep-water Gulf access pool home, perfectly positioned just minutes from Pine Island Sound and the Intracoastal Waterway. Offering easy access to back
St James City, FL
Living Area: 2016 Sqft.
3 Beds, 2 Baths
$999,500
Picture of 2281 8th Avenue
2281 8th Avenue
Must see this TURNKEY, newly furnished, tranquil bay waterfront property with immediate access to the intercoastal and abundance of wildlife. This beautiful home has captivating views of the secluded bay and Cape Coral and is located on desirable 8th Avenue in Saint James City. Everything you see wh
St James City, FL
Living Area: 1692 Sqft.
3 Beds, 2 Baths
$859,900
Picture of 2281 8th AVE
2281 8th AVE
Must see this TURNKEY, newly furnished, tranquil bay waterfront property with immediate access to the intercoastal and abundance of wildlife. This beautiful home has captivating views of the secluded bay and Cape Coral and is located on desirable 8th Avenue in Saint James City. Everything you see wh
ST. JAMES CITY, FL
Living Area: 1692 Sqft.
3 Beds, 2 Baths
$859,900
Picture of 2372 CHERIMOYA LANE
2372 CHERIMOYA LANE
Are you looking for the best boating and fishing experience in Florida? This home in Saint James, located just north of the Sanibel Causeway, is perfect for embracing a new boating lifestyle. It features a direct deep-water canal access and offers a large dock, a beautiful pool, impact windows, plan
ST JAMES CITY, FL
Living Area: 2328 Sqft.
3 Beds, 3 Baths
$995,000
Picture of 2372 Cherimoya Lane
2372 Cherimoya Lane
Experience true coastal luxury in this beautifully remodeled 3BD/3BA waterfront retreat in Saint James City with direct Gulf access—no bridges. Located just north of the Sanibel Causeway, this elevated oasis offers 2,383 sqft of open living, soaring ceilings, & 5 sets of impact sliding doors for s
St James City, FL
Living Area: 2383 Sqft.
3 Beds, 3 Baths
$995,000
Picture of 2372 Cherimoya LN
2372 Cherimoya LN
Experience true coastal luxury in this beautifully remodeled 3BD/3BA waterfront retreat in Saint James City with direct Gulf access—no bridges. Located just north of the Sanibel Causeway, this elevated oasis offers 2,383 sqft of open living, soaring ceilings, & 5 sets of impact sliding doors for s
ST. JAMES CITY, FL
Living Area: 2383 Sqft.
3 Beds, 3 Baths
$995,000
Picture of 2277 Sapodilla LN
2277 Sapodilla LN
Great Opportunity in St James City! Situated on the highly desirable south end of Pine Island, access to the Gulf of Mexico or the white sand beaches of Sanibel is just a short 10 min boat ride away! St James City has lots to offer within a quick golf cart ride, including several local restaurants,
ST. JAMES CITY, FL
Living Area: 1957 Sqft.
3 Beds, 2 Baths
$550,000
Picture of 2277 Sapodilla Lane
2277 Sapodilla Lane
Great Opportunity in St James City! Situated on the highly desirable south end of Pine Island, access to the Gulf of Mexico or the white sand beaches of Sanibel is just a short 10 min boat ride away! St James City has lots to offer within a quick golf cart ride, including several local restaurants,
St James City, FL
Living Area: 1957 Sqft.
3 Beds, 2 Baths
$550,000
Picture of 2389 Cherimoya LN
2389 Cherimoya LN
Seller is offering $10,000 in buyer concessions for rate buydown/closing cost. If you're looking for a home in Saint James City, this is it. When you first pull up, you'll notice the rock landscaping in the front yard, which makes for very low maintenance – no endless yard work here. Step inside,
ST. JAMES CITY, FL
Living Area: 1837 Sqft.
3 Beds, 2 Baths
$875,000
Picture of 2389 Cherimoya Lane
2389 Cherimoya Lane
Seller is offering $10,000 in buyer concessions for rate buydown/closing cost. If you're looking for a home in Saint James City, this is it. When you first pull up, you'll notice the rock landscaping in the front yard, which makes for very low maintenance – no endless yard work here. Step inside,
St James City, FL
Living Area: 1837 Sqft.
3 Beds, 2 Baths
$875,000
Picture of 2771 Teal Court
2771 Teal Court
This home has it all. It sits on a gorgeous interior bay with big views. You can safely keep your boats behind your house. It has a large dock with space for four boats with two boat lifts. There is a large backyard with a pool and spa with a paver patio. Below the home is a large carport for y
St James City, FL
Living Area: 3251 Sqft.
4 Beds, 4 Baths
$1,749,000
Picture of 2771 Teal CT
2771 Teal CT
This home has it all. It sits on a gorgeous interior bay with big views. You can safely keep your boats behind your house. It has a large dock with space for four boats with two boat lifts. There is a large backyard with a pool and spa with a paver patio. Below the home is a large carport for y
ST. JAMES CITY, FL
Living Area: 3251 Sqft.
4 Beds, 4 Baths
$1,749,000
Picture of 2690 Gull Court
2690 Gull Court
As you enter this unique custom home you will be surrounded by tropical colors accented with the warm tones of bamboo, cypress, and mahogany. The architecture and decor were inspired by the current owners' travels to the Keys, Caribbean, and South Pacific. The floor plan was designed with the reti
St James City, FL
Living Area: 3150 Sqft.
4 Beds, 4 Baths
$1,625,000
Picture of 2690 Gull CT
2690 Gull CT
As you enter this unique custom home you will be surrounded by tropical colors accented with the warm tones of bamboo, cypress, and mahogany. The architecture and decor were inspired by the current owners' travels to the Keys, Caribbean, and South Pacific. The floor plan was designed with the reti
ST. JAMES CITY, FL
Living Area: 3150 Sqft.
4 Beds, 4 Baths
$1,625,000

Points of Interest near Big Sister Key Preserve

Additional information

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