Realty.com
Buy

Start here

  • Homes for sale by state
  • Home buying tips
  • Before you start looking
  • The buying timeline

Afford it

  • Today's mortgage rates
  • Mortgage calculator
  • How much can I afford?
  • Get pre-approved

Make the deal

  • Writing a winning offer
  • Inspections & appraisals
  • Closing costs, itemized
  • Find a buyer's agent
Sell

Selling Options

  • What's my home worth?
  • Compare selling options
  • Get an instant cash offer
  • Buy before you sell

Resources

  • How selling works
  • When should I sell?
  • Home selling tips
  • Pricing your home
  • What's worth fixing first
  • Find a seller's agent
Home Loans
Find an Agent
Save searchAdvertiseSign In
Saved homesSaved searchesYour toursYour inquiriesRecently viewedAccount settings

Save search

Map layers

Safety

Safety & registry resources

Review official public-safety information for any area from these government sources:

  • U.S. Dept. of Justice National Sex Offender Public Website (NSOPW)
  • FBI: state sex-offender registry directory
Commercial Real Estate for Sale and Lease in Perryville, MO | Realty.com
Realty.com
Buy

Start here

  • Homes for sale by state
  • Home buying tips
  • Before you start looking
  • The buying timeline

Afford it

  • Today's mortgage rates
  • Mortgage calculator
  • How much can I afford?
  • Get pre-approved

Make the deal

  • Writing a winning offer
  • Inspections & appraisals
  • Closing costs, itemized
  • Find a buyer's agent
Save searchAdvertiseSign In
Saved homesSaved searchesYour toursYour inquiriesRecently viewedAccount settings
  • Residential
  • Rentals

33 listings
Sell

Selling Options

  • What's my home worth?
  • Compare selling options
  • Get an instant cash offer
  • Buy before you sell

Resources

  • How selling works
  • When should I sell?
  • Home selling tips
  • Pricing your home
  • What's worth fixing first
  • Find a seller's agent
Home Loans
Find an Agent
Save search

Commercial Real Estate for Sale and Lease in Perryville, MO

Commercial Real Estate for Sale and Lease in Perryville, MO

Hide Map
24 of 33 Listings
Map

Commercial Real Estate for Sale and Lease in Perryville, MO

24 of 33 Listings

  1. 1418 W Saint Joseph Street Suite 60 — photo7Active

    $900/mo

    0 bd · 0 ba · — sqft

    1418 W Saint Joseph Street Suite 60, Perryville, MO

    Devin Hoehn · AgriBuck Properties

  2. 1418 W Saint Joseph Street Suite 110 — photo8Active

    $900/mo

    0 bd · 0 ba · — sqft

    1418 W Saint Joseph Street Suite 110, Perryville, MO

    Devin Hoehn · AgriBuck Properties

  3. 1418 W Saint Joseph Street Suite 80 — photo4Active

    $1,000/mo

    0 bd · 0 ba · — sqft

    1418 W Saint Joseph Street Suite 80, Perryville, MO

    Devin Hoehn · AgriBuck Properties

  4. 700 S Kingshighway Street — photo30Active

    $169,900

    0 bd · 0 ba · 1,488 sqft

    700 S Kingshighway Street, Perryville, MO

    Eli Brown · RE/MAX Realty Experts

  5. 117 S Kingshighway Street — photo26Active

    $490,500

    0 bd · 0 ba · 780 sqft

    117 S Kingshighway Street, Perryville, MO

    Mina Hoehn · RE/MAX Realty Experts

  6. 1 Perryville Boulevard — photo13Active

    $607,464

    0 bd · 0 ba · — sqft

    1 Perryville Boulevard, Perryville, MO

    Amy Cates · RE/MAX Realty Experts

  7. 519 N Main Street — photo54Active

    $405,000

    0 bd · 0 ba · 4,099 sqft

    519 N Main Street, Perryville, MO

    Tracey Hagan · RE/MAX Realty Experts

  8. 805 N Main Street — photo31Active

    $235,000

    0 bd · 0 ba · 3,072 sqft

    805 N Main Street, Perryville, MO

    Kelly Brown · Ritter Real Estate

  9. 1004-B N Main — photo10Active

    $325,000

    0 bd · 0 ba · 6,000 sqft

    1004-B N Main, Perryville, MO

    Jennifer Janet · 573 Realty Group

  10. 4 Kiefner Street — photoPrice Reduced92Active

    $335,000

    0 bd · 0 ba · 4,594 sqft

    4 Kiefner Street, Perryville, MO

    Kelly Brown · Ritter Real Estate

  11. 317 S Kingshighway — photo19Active

    $1,950/mo

    0 bd · 0 ba · 3,890 sqft

    317 S Kingshighway, Perryville, MO

    Devin Hoehn · AgriBuck Properties

  12. 15 W Saint Joseph Street — photo48Active

    $699,900

    0 bd · 0 ba · 3,366 sqft

    15 W Saint Joseph Street, Perryville, MO

    Jacob Fish · EDGE Realty ERA Powered

  13. 1004 N Main Street — photoPrice Reduced36Active

    $575,000

    0 bd · 0 ba · 9,600 sqft

    1004 N Main Street, Perryville, MO

    Jennifer Janet · 573 Realty Group

  14. 2015 S Perryville Boulevard C & D — photo5Active

    $1,100/mo

    0 bd · 0 ba · — sqft

    2015 S Perryville Boulevard C & D, Perryville, MO

    Jennifer Janet · 573 Realty Group

  15. 119 N Jackson Street — photo71Active

    $695,000

    0 bd · 0 ba · — sqft

    119 N Jackson Street, Perryville, MO

    Devin Blandford · Area Properties Real Estate-Midsouth

  16. 875 Pcr 500 — photo28Active

    $745,000

    0 bd · 0 ba · — sqft

    875 Pcr 500, Perryville, MO

    Alexandria Lueders · Ritter Real Estate

  17. 7971 Hwy B — photoPrice Reduced4Active

    $199,000

    0 bd · 0 ba · — sqft

    7971 Hwy B, Perryville, MO

    Lorrain Wibbenmeyer · Preferred Realty

  18. 628 Old Saint Marys Road — photoPrice Reduced29Active

    $6/mo

    0 bd · 0 ba · 16,750 sqft

    628 Old Saint Marys Road, Perryville, MO

    Chris Cole · Lorimont L.C.

  19. 456 Semo Lane — photo12Active

    $1,500,000

    0 bd · 0 ba · 21,510 sqft

    456 Semo Lane, Perryville, MO

    Tom Kelsey · Lorimont L.C.

  20. 351 N Perryville Boulevard — photoPrice Reduced13Active

    $429,900

    0 bd · 0 ba · — sqft

    351 N Perryville Boulevard, Perryville, MO

    Jennifer Janet · 573 Realty Group

  21. 221 W Saint Joseph Street — photo46Active

    $560,000

    0 bd · 0 ba · 3,143 sqft

    221 W Saint Joseph Street, Perryville, MO

    Jacob Fish · EDGE Realty ERA Powered

  22. 1512 Old St Mary's Road — photoPrice Reduced63Active

    $555,000

    0 bd · 0 ba · 1,727 sqft

    1512 Old St Mary's Road, Perryville, MO

    Jennifer Janet · 573 Realty Group

  23. 304 W South Street — photo31Active

    $550,000

    0 bd · 0 ba · — sqft

    304 W South Street, Perryville, MO

    Jacob Fish · EDGE Realty ERA Powered

  24. 104-110 N Jackson Street — photo65Active

    $3,030,000

    0 bd · 0 ba · 20,600 sqft

    104-110 N Jackson Street, Perryville, MO

    Jacob Fish · EDGE Realty ERA Powered

12
Realty.com

L. Custen Realty, Inc. d/b/a Realty.com/L. Custen Realty CT, LLC d/b/a Realty.com (Tom O’Leary-Broker)(CT properties only), 8323 Southwest Freeway, Suite 900, Houston, Texas 77074

Equal Housing OpportunityEqual Housing Lender

The information provided by this website is for the personal, non-commercial use of consumers and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Listing data is derived from various Multiple Listing Services; each source MLS and its required disclaimer are shown with the listings on the applicable page. Realty.com is an independently owned and operated brokerage.

© 2026 Realty.com. All rights reserved.·Privacy·Terms·California Privacy Rights·Accessibility·Licensing

Listing data & MLS disclosures

MARIS MLS
Based on information submitted to the MLS GRID as of 2026-10-16 17:01:39 UTC. All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information.

Perryville, MO community profile

Population
8,649
Median income
$56,818
Housing units
3,739
People per sq. mi.
21.6
Area
399.6 sq. mi.

Source: HJN community data