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27 listings

Commercial Real Estate for Sale and Lease in Opelousas, LA

Commercial Real Estate for Sale and Lease in Opelousas, LA

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24 of 27 Listings
Map

Commercial Real Estate for Sale and Lease in Opelousas, LA

24 of 27 Listings

  1. 420 N Main Street — photo8
Active

$189,000

— bd · 2 ba · 1,400 sqft

420 N Main Street, Opelousas, LA

Trinh Huynh · Keller Williams Realty Acadiana

  • 505 S Court Street — photo21Active

    $250,000

    — bd · 2 ba · 3,642 sqft

    505 S Court Street, Opelousas, LA

    Lana Soileau · Real Broker, LLC

  • 2010 Cummings Street — photo28Active

    $150,000

    — bd · 3 ba · 1,228 sqft

    2010 Cummings Street, Opelousas, LA

    Wendy Savoy · Coldwell Banker Trahan Real Estate Group

  • 628 S Railroad Avenue — photo19Active

    $45,000

    — bd · 2 ba · 3,200 sqft

    628 S Railroad Avenue, Opelousas, LA

    Crystal Brooks · Reality Realty, LLC

  • 1427 W Linwood Drive — photo34Active

    $750,000

    — bd · 3 ba · 19,125 sqft

    1427 W Linwood Drive, Opelousas, LA

    Chris Lejeune · Real Broker, LLC

  • 331 E Jefferson Street — photo18Active

    $349,500

    — bd · 1 ba · 3,813 sqft

    331 E Jefferson Street, Opelousas, LA

    Chris Lejeune · Real Broker, LLC

  • 232 E Leonard Avenue — photo7Active

    $175,000

    — bd · 2 ba · 3,420 sqft

    232 E Leonard Avenue, Opelousas, LA

    Lori Lege' · Keller Williams Realty Acadiana

  • 523 S Main Street — photo18Active

    $110,000

    — bd · 1 ba · 1,500 sqft

    523 S Main Street, Opelousas, LA

    Lori Lege' · Keller Williams Realty Acadiana

  • 8188 Louisiana 182 — photo20Active

    $199,999

    — bd · — ba · 2,000 sqft

    8188 Louisiana 182, Opelousas, LA

    Dwayne P Hargroder · Hargroder Real Estate Group

  • 129 W Landry Street — photoPrice Reduced10Active

    $147,000

    — bd · 1 ba · 580 sqft

    129 W Landry Street, Opelousas, LA

    Colby Richard · Real Broker, LLC

  • 1004 Creswell Lane — photo16Active

    $1,700/mo

    — bd · 1 ba · 1,665 sqft

    1004 Creswell Lane, Opelousas, LA

    Raymond A Aguillard · DCG/Aguillard Realty

  • 2218 George Drive — photoPrice Reduced23Active

    $299,000

    — bd · — ba · 2,822 sqft

    2218 George Drive, Opelousas, LA

    Dwayne P Hargroder · Hargroder Real Estate Group

  • 1802 W Landry Street — photo7Active

    $625,000

    — bd · — ba · 37,000 sqft

    1802 W Landry Street, Opelousas, LA

    Paul Arceneaux · Arceneaux Real Estate, LLC

  • 119 E Landry Street — photoPrice Reduced25Active

    $1,500,000

    — bd · — ba · 81,217 sqft

    119 E Landry Street, Opelousas, LA

    Dwayne P Hargroder · Hargroder Real Estate Group

  • 103 E Bellevue Street — photo6Active

    $950,000

    — bd · — ba · 13,060 sqft

    103 E Bellevue Street, Opelousas, LA

    Dwayne P Hargroder · Hargroder Real Estate Group

  • 135 E Landry Street — photo6Active

    $600,000

    — bd · — ba · 6,993 sqft

    135 E Landry Street, Opelousas, LA

    Dwayne P Hargroder · Hargroder Real Estate Group

  • 828 Creswell Lane — photoPrice Reduced21Active

    $250,000

    — bd · 5 ba · 4,516 sqft

    828 Creswell Lane, Opelousas, LA

    Chad Trahan · Coldwell Banker Trahan Real Estate Group

  • 8599 Highway 182 B — photo6Active

    $750/mo

    — bd · — ba · 2,940 sqft

    8599 Highway 182 B, Opelousas, LA

    Spencer Cobb · The Gleason Group

  • 3383 I 49 S Service Road — photo14Active

    $2,750/mo

    — bd · 1 ba · 4,800 sqft

    3383 I 49 S Service Road, Opelousas, LA

    Spencer Cobb · The Gleason Group

  • 126 E Bellevue Street — photoPrice Reduced12Active

    $299,000

    — bd · 2 ba · 5,000 sqft

    126 E Bellevue Street, Opelousas, LA

    Colby Richard · Real Broker, LLC

  • 507 N Market Street — photoPrice Reduced19Active

    $187,000

    — bd · 3 ba · 2,371 sqft

    507 N Market Street, Opelousas, LA

    Ann Porche · Compass

  • 816 Creswell Lane — photo22Active

    $4,697/mo

    — bd · 5 ba · 4,326.36 sqft

    816 Creswell Lane, Opelousas, LA

    Lana Soileau · Real Broker, LLC

  • 905 N Main Street — photo21Active

    $179,900

    — bd · 1 ba · 5,400 sqft

    905 N Main Street, Opelousas, LA

    Dwayne P Hargroder · Hargroder Real Estate Group

  • 823 W Vine Street — photoPrice Reduced27Active

    $110,000

    — bd · 1 ba · 2,487 sqft

    823 W Vine Street, Opelousas, LA

    Holly B Cange · Real Broker, LLC

  • 12
    Realty.com

    L. Custen Realty, Inc. d/b/a Realty.com/L. Custen Realty CT, LLC d/b/a Realty.com (Tom O’Leary-Broker)(CT properties only), 8323 Southwest Freeway, Suite 900, Houston, Texas 77074

    Equal Housing OpportunityEqual Housing Lender

    The information provided by this website is for the personal, non-commercial use of consumers and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Listing data is derived from various Multiple Listing Services; each source MLS and its required disclaimer are shown with the listings on the applicable page. Realty.com is an independently owned and operated brokerage.

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    Listing data & MLS disclosures

    REALTOR Association of Acadiana
    The data relating to real estate for sale on this website comes in part from the Internet Data exchange (IDX) program of the REALTOR® Association of Acadiana. IDX information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Information deemed reliable but not guaranteed. Copyright ©2026 REALTOR® Association of Acadiana. All rights reserved.

    Opelousas, LA community profile

    Population
    15,520
    Median income
    $38,644
    Housing units
    6,992
    People per sq. mi.
    89
    Area
    174.3 sq. mi.

    Source: HJN community data

    Commercial Real Estate for Sale and Lease in Opelousas, LA | Realty.com