Realty.com
Buy

Start here

  • Homes for sale by state
  • Home buying tips
  • Before you start looking
  • The buying timeline

Afford it

  • Today's mortgage rates
  • Mortgage calculator
  • How much can I afford?
  • Get pre-approved

Make the deal

  • Writing a winning offer
  • Inspections & appraisals
  • Closing costs, itemized
  • Find a buyer's agent
Sell

Selling Options

  • What's my home worth?
  • Compare selling options
  • Get an instant cash offer
  • Buy before you sell

Resources

  • How selling works
  • When should I sell?
  • Home selling tips
  • Pricing your home
  • What's worth fixing first
  • Find a seller's agent
Home Loans
Find an Agent
Save searchAdvertiseSign In
Saved homesSaved searchesYour toursYour inquiriesRecently viewedAccount settings

Save search

Map layers

Safety

Safety & registry resources

Review official public-safety information for any area from these government sources:

  • U.S. Dept. of Justice National Sex Offender Public Website (NSOPW)
  • FBI: state sex-offender registry directory
Single-Family Homes in Santee, SC
Realty.com
Buy

Start here

  • Homes for sale by state
  • Home buying tips
  • Before you start looking
  • The buying timeline

Afford it

  • Today's mortgage rates
  • Mortgage calculator
  • How much can I afford?
  • Get pre-approved

Make the deal

  • Writing a winning offer
  • Inspections & appraisals
  • Closing costs, itemized
  • Find a buyer's agent
Save searchAdvertiseSign In
Saved homesSaved searchesYour toursYour inquiriesRecently viewedAccount settings
  • Rentals
  • Commercial

48 listings
Sell

Selling Options

  • What's my home worth?
  • Compare selling options
  • Get an instant cash offer
  • Buy before you sell

Resources

  • How selling works
  • When should I sell?
  • Home selling tips
  • Pricing your home
  • What's worth fixing first
  • Find a seller's agent
Home Loans
Find an Agent
Save search

Single-Family Homes in Santee, SC

Single-Family Homes in Santee, SC

Hide Map
21 of 48 Listings
Map

Single-Family Homes in Santee, SC

21 of 48 Listings

Your local brokerage

TO

Thomas O'Leary

Realty.com

Lic. #98777

Call Thomas
  1. 792 Sinker Lane — photoNew35Active

    $309,990

    3 bd · 3 ba · 1,910 sqft

    792 Sinker Lane, Santee, SC

    Peter Firehock · Ryan Homes

  2. 133 2nd Street — photo30Active

    $189,900

    2 bd · 1 ba · 1,092 sqft

    133 2nd Street, Santee, SC

    Brian Deweese · Carolina One Real Estate

  3. 166 William Clark Boulevard — photo23Active

    $252,000

    5 bd · 4 ba · 2,646 sqft

    166 William Clark Boulevard, Santee, SC

    Mickey Durham · Mickey D Durham Realty

  4. 1015 Chapel Branch Road — photo41Active

    $510,000

    3 bd · 2 ba · 1,401 sqft

    1015 Chapel Branch Road, Santee, SC

    Hannah Detwiler · ERA Wilder Realty-Santee

  5. 126 Cooper Drive — photo40Active

    $469,000

    3 bd · 2 ba · 2,084 sqft

    126 Cooper Drive, Santee, SC

    Pam Clayton · The Litchfield Company Christies International Real Estate

  6. 221 Friendship Road — photo8Active

    $170,000

    3 bd · 2 ba · 1,813 sqft

    221 Friendship Road, Santee, SC

    Wilfred Drakes · EXIT Empowerment Realty

  7. 491 Chapel Creek Drive — photo40Active

    $570,000

    3 bd · 3 ba · 3,051 sqft

    491 Chapel Creek Drive, Santee, SC

    Becky Armstrong · Carolina Properties at Lake Marion

  8. 142 Shuler Street — photoPrice Reduced16Active

    $139,900

    2 bd · 2 ba · 2,640 sqft

    142 Shuler Street, Santee, SC

    Rosemarie Elliott · Home & Land Pros

  9. 764 Striped Bass Court — photo13Active

    $239,000

    3 bd · 2 ba · 1,183 sqft

    764 Striped Bass Court, Santee, SC

    Scott Clark · Santee Associates

  10. 4 Andre Michaux Road — photo38Active

    $190,000

    2 bd · 2 ba · 1,301 sqft

    4 Andre Michaux Road, Santee, SC

    Mark Nobles · Jeff Cook Real Estate LPT Realty

  11. 752 Striped Bass Court — photo29Active

    $250,000

    3 bd · 3 ba · 1,517 sqft

    752 Striped Bass Court, Santee, SC

    Katie Stevens Grout · D R Horton Inc

  12. 1010 Park Drive — photo54Active

    $399,900

    3 bd · 3 ba · 2,141 sqft

    1010 Park Drive, Santee, SC

    Brandon Ray · Carolina One Real Estate

  13. 271 Boo Circle — photo12Active

    $221,900

    3 bd · 1 ba · 1,025 sqft

    271 Boo Circle, Santee, SC

    Jackie Lee · ERA Wilder Realty Inc.

  14. 700 Striped Bass Court — photoPrice Reduced26Active

    $256,415

    3 bd · 3 ba · 1,518 sqft

    700 Striped Bass Court, Santee, SC

    Katie Stevens Grout · D R Horton Inc

  15. 130 2nd Street — photoPrice Reduced52Active

    $230,000

    3 bd · 2 ba · 1,580 sqft

    130 2nd Street, Santee, SC

    Cj Mccormick · AgentOwned Realty

  16. 176 William Clark Boulevard — photo32Active

    $367,605

    3 bd · 3 ba · 2,482 sqft

    176 William Clark Boulevard, Santee, SC

    Katie Stevens Grout · D R Horton Inc

  17. 143 William Clark Boulevard — photoPrice Reduced22Active

    $219,900

    4 bd · 2 ba · 1,827 sqft

    143 William Clark Boulevard, Santee, SC

    Rocky Milligan · Transit Realty Florence

  18. 9792 Old Number Six Highway — photoPrice Reduced44Active

    $469,000

    3 bd · 2 ba · 1,539 sqft

    9792 Old Number Six Highway, Santee, SC

    Scott Clark · Santee Associates Realty

  19. 139 Congaree Court — photoPrice Reduced27Active

    $219,000

    3 bd · 2 ba · 1,183 sqft

    139 Congaree Court, Santee, SC

    Matthew Sceviour · Jeff Cook Real Estate LPT Realty

  20. 126 Congaree Court — photo43Active

    $250,000

    4 bd · 2 ba · 1,482 sqft

    126 Congaree Court, Santee, SC

    Dianne Rodgers-peters · Carolina One Real Estate

  21. 109 Birdie Court — photoPrice Reduced62Active

    $315,000

    2 bd · 2 ba · 1,444 sqft

    109 Birdie Court, Santee, SC

    Ianna Fincher · Carolina One Real Estate

12

About Single-Family Homes in Santee, SC

Single-Family Homes in Santee, SC: 48 active listings as of November 4, 2026, 22:29 UTC.

Realty.com

L. Custen Realty, Inc. d/b/a Realty.com/L. Custen Realty CT, LLC d/b/a Realty.com (Tom O’Leary-Broker)(CT properties only), 8323 Southwest Freeway, Suite 900, Houston, Texas 77074

Equal Housing OpportunityEqual Housing Lender

The information provided by this website is for the personal, non-commercial use of consumers and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Listing data is derived from various Multiple Listing Services; each source MLS and its required disclaimer are shown with the listings on the applicable page. Realty.com is an independently owned and operated brokerage.

© 2026 Realty.com. All rights reserved.·Privacy·Terms·California Privacy Rights·Accessibility·Licensing

Listing data & MLS disclosures

CHS Regional MLS (CTAR)
The data relating to real estate for sale on this website comes in part from the Broker Reciprocity Program of the Charleston Trident Association of REALTORS®/Charleston Trident Multiple Listing Service. Those properties marked with the Broker Reciprocity logo are provided courtesy of the Charleston Trident MLS Broker Reciprocity Database. Information being provided is for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Data is deemed reliable but is not guaranteed accurate by the MLS. Any use of search facilities of data on the site, other than by a consumer looking to purchase real estate, is prohibited. Information deemed reliable but not guaranteed. Copyright © 2026 Charleston Trident Association of REALTORS®. All Rights Reserved.
Consolidated MLS (Columbia MLS)
The information being provided is for the consumer's personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumer may be interested in purchasing. Any information relating to real estate for sale referenced on this web site comes from the Internet Data Exchange (IDX) program of the Consolidated MLS®. This web site may reference real estate listing(s) held by a brokerage firm other than the broker and/or agent who owns this web site. The accuracy of all information, regardless of source, including but not limited to square footages and lot sizes, is deemed reliable but not guaranteed and should be personally verified through personal inspection by and/or with the appropriate professionals. Copyright, Consolidated MLS®
Sumter Board of REALTORS®
Listing information provided by Sumter Board of REALTORS®.

Santee, SC community profile

Population
779
Median income
$56,667
Housing units
398
People per sq. mi.
11.8
Area
66 sq. mi.

Source: HJN community data

Santee housing market

September 2026 · This period is still settling

Selling at 100.0% of asking price

Sales here are closing essentially at asking. MLS · 10 sales · as of Sep 30, 2026

Homes on the market · MLS, as of Sep 27, 2026

Median list price
$268,495
Homes for sale
56

Housing stock — every home in the area, not only the ones selling or listed · Assessor records, as of Sep 2, 2026

Median home size
1,536 sq. ft.
  • Your local brokerage

    TO

    Thomas O'Leary

    Realty.com

    Lic. #98777

    Call Thomas