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Commercial Real Estate for Sale and Lease in Salem, VA | Realty.com
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Start here

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  • Before you start looking
  • The buying timeline

Afford it

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Review official public-safety information for any area from these government sources:

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Sell

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  • Compare selling options
  • Get an instant cash offer
  • Buy before you sell

Resources

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15 listings

Commercial Real Estate for Sale and Lease in Salem, VA

Commercial Real Estate for Sale and Lease in Salem, VA

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15 Listings
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Commercial Real Estate for Sale and Lease in Salem, VA

15 Listings

  1. 2050 E Main St — photo13Active

    $525,000

    — bd · 1 ba · — sqft

    2050 E Main St, Salem, VA

    THOMAS SAMUEL TURNER · EDWIN C HALL ASSOCIATES INC

  2. 1929 Apperson Dr — photo37Active

    $624,950

    — bd · — ba · — sqft

    1929 Apperson Dr, Salem, VA

    GAVIN MILES HOLLINGSWORTH · EDWIN C HALL ASSOCIATES INC

  3. 1403 S Colorado St — photo46Active

    $275,000

    — bd · 1 ba · — sqft

    1403 S Colorado St, Salem, VA

    EGON M HOFMANN · BARKER REALTY CO

  4. 501 Roanoke Blvd — photo28Active

    $447,500

    — bd · — ba · — sqft

    501 Roanoke Blvd, Salem, VA

    GAYE A CLINGENPEEL · TOWN & COUNTRY REALTY OF FRANKLIN CO

  5. 1940 W Main St — photo6Active

    $1,250,000

    — bd · — ba · — sqft

    1940 W Main St, Salem, VA

    NEAL C WALL · JMAX PROPERTY MANAGEMENT LLC

  6. 4190 W Main St — photo92Active

    $549,000

    — bd · — ba · — sqft

    4190 W Main St, Salem, VA

    FRANK KREGLOE · KELLER WILLIAMS REALTY - NRV

  7. 1930 Braeburn Dr — photo1Active

    $649,500

    — bd · 8 ba · — sqft

    1930 Braeburn Dr, Salem, VA

    HENRY SCHOLZ IV · MKB, REALTORS®

  8. 2730 W Main St — photo6Active

    $309,000

    — bd · — ba · — sqft

    2730 W Main St, Salem, VA

    REINA HERNANDEZ · REAL BROKER LLC - MCLEAN

  9. 824 Iowa St — photo8Active

    $195,000

    — bd · — ba · — sqft

    824 Iowa St, Salem, VA

    KRISTA H VANNOY · WALDVOGEL COMMERCIAL PROPERTIES

  10. 2746 W Main St — photo5Active

    $1,935,000

    — bd · — ba · — sqft

    2746 W Main St, Salem, VA

    DORIS S SMITH · BARKER REALTY CO

  11. 0 West Main St — photo3Active

    $180,000

    — bd · — ba · — sqft

    0 West Main St, Salem, VA

    BONNIE LYNN JOYCE · CENTURY 21 WAMPLER REALTY

  12. 904 Apperson Dr — photo13Active

    $495,000

    — bd · 1 ba · — sqft

    904 Apperson Dr, Salem, VA

    KRISTA H VANNOY · WALDVOGEL COMMERCIAL PROPERTIES

  13. 1532 Apperson Dr — photo11Active

    $425,000

    — bd · — ba · — sqft

    1532 Apperson Dr, Salem, VA

    WILL EDWARD HENRITZE · POE & CRONK REAL ESTATE GROUP

  14. 1540 Apperson Dr — photo13Active

    $340,000

    — bd · — ba · — sqft

    1540 Apperson Dr, Salem, VA

    WILL EDWARD HENRITZE · POE & CRONK REAL ESTATE GROUP

  15. 901 S Colorado St — photo5Active

    $475,000

    — bd · — ba · — sqft

    901 S Colorado St, Salem, VA

    DAVID MCCRAY · MKB, REALTORS®

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Listing data & MLS disclosures

Roanoke Valley Association of REALTORS
Although the Multiple Listing Service of The Roanoke Valley is the single source for these listings, listing data appearing on this website does not necessarily reflect the entirety of all available listings within the Multiple Listing Service. All listing data is refreshed daily, but its accuracy is subject to market changes. All copyrights and intellectual property rights are the exclusive property of the Multiple Listing Service of The Roanoke Valley. Whether obtained from a search result or otherwise, visitors to this website may only use this listing data for their personal, noncommercial benefit. The unauthorized retrieval or use of this listing data is prohibited. All information is deemed reliable but not guaranteed, and should be independently verified. Copyright © 2026 Multiple Listing Service of The Roanoke Valley. All rights reserved.

Salem, VA community profile

Population
26,009
Median income
$71,541
Housing units
11,130
People per sq. mi.
247.5
Area
105.1 sq. mi.

Source: HJN community data