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Commercial Real Estate for Sale and Lease in Salem, MO | Realty.com
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Buy

Start here

  • Homes for sale by state
  • Home buying tips
  • Before you start looking
  • The buying timeline

Afford it

  • Today's mortgage rates
  • Mortgage calculator
  • How much can I afford?
  • Get pre-approved

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  • Closing costs, itemized
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  • Residential
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Safety & registry resources

Review official public-safety information for any area from these government sources:

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Sell

Selling Options

  • What's my home worth?
  • Compare selling options
  • Get an instant cash offer
  • Buy before you sell

Resources

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  • Pricing your home
  • What's worth fixing first
  • Find a seller's agent
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12 listings

Commercial Real Estate for Sale and Lease in Salem, MO

Commercial Real Estate for Sale and Lease in Salem, MO

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12 Listings
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Commercial Real Estate for Sale and Lease in Salem, MO

12 Listings

  1. 404 W Rolla Road — photo39Active

    $280,000

    — bd · — ba · — sqft

    404 W Rolla Road, Salem, MO

    Mark Kerivan · Murney Associates - Primrose

  2. 117 W 4th Street — photo9Active

    $380,000

    — bd · — ba · — sqft

    117 W 4th Street, Salem, MO

    Shirley Manthey · Century 21 South Central Realty

  3. 905-909 E Scenic Rivers Boulevard — photo34Active

    $800,000

    — bd · — ba · — sqft

    905-909 E Scenic Rivers Boulevard, Salem, MO

    Lance Lewis · EXP Realty LLC

  4. 305 W Scenic Rivers Boulevard — photo32Active

    $375,000

    — bd · — ba · — sqft

    305 W Scenic Rivers Boulevard, Salem, MO

    Taylor Friend · EXP Realty, LLC

  5. 107 E 4th Street — photo1Active

    $85,000

    — bd · — ba · — sqft

    107 E 4th Street, Salem, MO

    Richard Pogue · VIP Properties

  6. 201 E Roosevelt Street — photoPrice Reduced11Active

    $144,900

    — bd · — ba · — sqft

    201 E Roosevelt Street, Salem, MO

    Beth Frizzell · Century 21 South Central Realty

  7. 510 N Main Street — photo18Active

    $250,000

    — bd · — ba · — sqft

    510 N Main Street, Salem, MO

    Jacqueline Stuart · Ozark Elements Realty, LLC

  8. 600 East Hwy 32 — photo24Active

    $300,000

    — bd · — ba · — sqft

    600 East Hwy 32, Salem, MO

    Jan Watson · VIP Properties

  9. 404 E Scenic Rivers Boulevard — photoPrice Reduced5Active

    $169,900

    — bd · — ba · — sqft

    404 E Scenic Rivers Boulevard, Salem, MO

    Peggy Ann Bryce · Salem Properties

  10. 300 S Main Street — photoPrice Reduced18Active

    $480,000

    — bd · — ba · — sqft

    300 S Main Street, Salem, MO

    Becky Wilson · Century 21 South Central Realty

  11. 000 E Scenic Rivers Boulevard — photo7Active

    $209,900

    — bd · — ba · — sqft

    000 E Scenic Rivers Boulevard, Salem, MO

    Kent Sturgeon · ReeceNichols - Springfield

  12. 1 S Main Street — photo12Active

    $305,000

    — bd · — ba · 6,934 sqft

    1 S Main Street, Salem, MO

    Matthew Woessner · Investment Realty, Inc.

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Listing data & MLS disclosures

MARIS MLS
Based on information submitted to the MLS GRID as of 2026-08-31 15:37:14 UTC. All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information.
Southern Missouri Regional MLS
The data relating to real estate for sale on this web page comes in part from the Internet Data Exchange (IDX) of Southern Missouri Regional MLS. Real estate listings held by Brokerage firms other than Realty.com are marked with the IDX logo and detailed information about them includes the name of the listing Brokers. The information being provided is for consumers' personal, noncommercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The information being provided is deemed reliable but not guaranteed, and all information should be verified by the consumer. Any representation that a website contains all listings shall only mean that the website contain all listing available to the public through the IDX data feed. There may be other properties offered through a REALTOR® that have not been displayed on this site. Information deemed reliable but not guaranteed. Copyright © 2026 Southern Missouri Regional MLS. All Rights Reserved.

Salem, MO community profile

Population
4,702
Median income
$42,160
Housing units
2,372
People per sq. mi.
6.8
Area
686.8 sq. mi.

Source: HJN community data