Start here

Homes for sale by state
Home buying tips
Before you start looking
The buying timeline

Afford it

Today's mortgage rates
Mortgage calculator
How much can I afford?
Get pre-approved

Make the deal

Writing a winning offer
Inspections & appraisals
Closing costs, itemized
Find a buyer's agent

Selling Options

What's my home worth?
Compare selling options
Get an instant cash offer
Buy before you sell

Resources

How selling works
When should I sell?
Home selling tips
Pricing your home
What's worth fixing first
Find a seller's agent

Save search Advertise Sign In

Saved homes Saved searches Your tours Your inquiries Recently viewed Account settings

Registered offenders on the map

Show registered offenders

Registered offenders on the map

Show registered offenders

Safety & registry resources

Review official public-safety information for any area from these government sources:

U.S. Dept. of Justice National Sex Offender Public Website (NSOPW)
FBI: state sex-offender registry directory

Start here

Homes for sale by state
Home buying tips
Before you start looking
The buying timeline

Afford it

Today's mortgage rates
Mortgage calculator
How much can I afford?
Get pre-approved

Make the deal

Writing a winning offer
Inspections & appraisals
Closing costs, itemized
Find a buyer's agent

Save search Advertise Sign In

Saved homes Saved searches Your tours Your inquiries Recently viewed Account settings

Registered offenders on the map

Show registered offenders

Selling Options

What's my home worth?
Compare selling options
Get an instant cash offer
Buy before you sell

Resources

How selling works
When should I sell?
Home selling tips
Pricing your home
What's worth fixing first
Find a seller's agent

249 listings

Homes for Sale in 49221, MI

Homes for Sale in 49221, MI

15 of 249 Listings

Homes for Sale in 49221, MI

15 of 249 Listings

28Active

$300,800

3 bd · 2 ba · 1,268 sqft

2022 Green Acres Drive, Adrian, MI

Donald Page · DJW Realty, LLC

Price Reduced19Active

$320,300

3 bd · 3 ba · 1,648 sqft

2018 Green Acres Drive, Adrian, MI

Donald Page · DJW Realty, LLC

$425,000

3 bd · 2 ba · 2,056 sqft

2150 Southard Highway, Adrian City, MI

Lesley Dempsey · Howard Hanna Real Estate Services-Adrian

$269,900

4 bd · 2 ba · 1,396 sqft

972 Gettysburg Drive, Adrian City, MI

Kay Buenaflor Prong · Howard Hanna Real Estate Services-Tecumseh

$449,000

3 bd · 2 ba · 1,800 sqft

3000 Country Club Road, Adrian, MI

Elijah Waynick · W3 Homes LLC

Price Reduced42Active

$233,000

3 bd · 2 ba · 2,176 sqft

434 W Westwood Drive, Adrian City, MI

Mason Erpelding · The Wagley Group

$449,000

3 bd · 2 ba · 1,800 sqft

3000 Country Club Road Blk, Adrian, MI

Elijah Waynick · W3 Homes LLC

$449,000

3 bd · 2 ba · 1,800 sqft

3000 Country Club Road Blk, Adrian, MI

Elijah Waynick · W3 Homes LLC

$449,000

3 bd · 2 ba · 1,800 sqft

3000 Country Club Road, Adrian, MI

Elijah Waynick · W3 Homes LLC

$328,000

3 bd · 3 ba · 1,780 sqft

2024 Green Acres Drive, Adrian, MI

Donald Page · DJW Realty, LLC

$110,000

2 bd · 2 ba · 980 sqft

7373 S Adrian Highway, Adrian City, MI

Sheila Ruttkofsky · Goedert Real Estate - Adr

$138,000

3 bd · 2 ba · 1,171 sqft

629 S Winter Street, Adrian City, MI

Sarah Buku · Grata Domum Realty, LLC

$229,000

3 bd · 2 ba · 2,080 sqft

1229 University Avenue, Adrian City, MI

Kyle Metdepenningen · The Wagley Group

$99,900

3 bd · 1 ba · 1,049 sqft

598 S Main Street, Adrian, MI

Drake Blazevski · RE/MAX Platinum

Price Reduced62Active

$649,900

4 bd · 3 ba · 3,226 sqft

4450 Bent Oak Highway, Adrian Township, MI

Danielle Strickler · Key Realty One LLC in Monroe

1…3 4 5…11

L. Custen Realty, Inc. d/b/a Realty.com/L. Custen Realty CT, LLC d/b/a Realty.com (Tom O’Leary-Broker)(CT properties only), 8323 Southwest Freeway, Suite 900, Houston, Texas 77074

The information provided by this website is for the personal, non-commercial use of consumers and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Listing data is derived from various Multiple Listing Services; each source MLS and its required disclaimer are shown with the listings on the applicable page. Realty.com is an independently owned and operated brokerage.

© 2026 Realty.com. All rights reserved.PrivacyTermsCalifornia Privacy RightsAccessibilityLicensing

Listing data & MLS disclosures

MiRealSource: Provided through IDX via MiRealSource. Courtesy of MiRealSource Shareholder. The information published and disseminated by MiRealSource is communicated verbatim, without change by MiRealSource, as filed with MiRealSource by its members. The accuracy of all information, regardless of source, is not guaranteed or warranted. All information should be independently verified. Copyright [current year] MiRealSource. All rights reserved. The information provided hereby constitutes proprietary information of MiRealSource, Inc. and its shareholders, affiliates and licensees and may not be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, scanning or any information storage and retrieval system, without written permission from MiRealSource, Inc.
Realcomp: IDX provided courtesy of Realcomp II Ltd. via Realty.com and Realcomp MLS, ©2026 Realcomp II Ltd. Shareholders The accuracy of all information, regardless of source, is not guaranteed or warranted. All information should be independently verified. Any use of search facilities of data on the site, other than by a consumer looking to purchase real estate, is prohibited.
Southwestern Michigan Association of REALTORS: The properties on this website come in part from the Broker Reciprocity Program of the Member MLS's of the Michigan Regional Information Center. Information Deemed Reliable But Not Guaranteed. The firm operating this website does not display the entire MLS, MichRIC, LLC, Broker Reciprocity database on this website. Any use of search facilities of data on the site, other than by a consumer looking to purchase real estate, is prohibited. Information deemed reliable but not guaranteed. Copyright ©2026 Michigan Regional Information Center. All Rights Reserved.

49221, MI Homes for Sale — Page 4 | Realty.com

Nearby areas

ZIP codes

49203 (332)
48176 (254)
48108 (191)
49201 (185)
49230 (143)
49286 (86)
48158 (80)
48103 (75)

Cities

Jackson (357)
Ann Arbor (211)
Saline (153)
Adrian (143)
Brooklyn (93)

Jackson City (92)

Pittsfield Charter Township (92)

Ann Arbor City (69)